Table 1.
RCTs comparing letrozole versus clomiphene as first line for anovulatory women
| Sl no |
Authors | Study design |
Treatment arms |
Numbers cycles |
Endometrial thickness (mm) |
Ovulation rates (%) |
Pregnancy rates (%) |
|---|---|---|---|---|---|---|---|
| 1 | Atay V et al. [9] Turkey, 2006 |
RCT | Letrozole 2.5 mg vs. Clomiphene 100 mg |
51 vs. 55 |
8.4 +/- 1.8 vs. 5.2 +/- 1.2 |
82.4 vs. 63.6 |
21.6 vs. 9.1 |
| 2 | Bayar U et al. [10] Turkey, 2006 |
RCT | Letrozole 2.5 mg vs. Clomiphene 100 mg |
99 vs. 95 |
8# vs. 8# |
65.7 vs. 74.7 |
9.1 vs. 7.4 |
| 3 | Badawy A et al. [11] Egypt, 2009 |
RCT | Letrozole 5 mg vs. Clomiphene 100 mg |
540 vs. 523 |
8.1+/-0.2 vs. 9.2+/-0.7 |
67.5 vs. 70.9 |
15.1 vs. 17.9 |
# Values represent median