Table 1.
Baseline demographic and other characteristics of the HEMO study cohort in the study presented here
| Baseline Characteristic | Quartile of Percent of Kinetic Modeling Sessions with Intradialytic Hypotension during the Period from Baseline to 4 Months |
||||
|---|---|---|---|---|---|
| Q1 n = 529 | Q2 n = 205 | Q3 n = 319 | Q4 n = 365 | Pa | |
| Age, years, mean (SD) | 56.0 (14.6) | 55.4 (14.8) | 59.2 (12.7) | 59.0 (13.0) | <0.0001 |
| Female sex, % | 44.6 | 56.1 | 58.9 | 66.6 | <0.0001 |
| Black race, % | 61.4 | 68.1 | 64.6 | 68.2 | 0.06 |
| Arteriovenous access type, % | 43.7 | 36.1 | 34.2 | 28.0 | <0.001 |
| fistula | 56.3 | 63.9 | 65.8 | 72.0 | |
| graft | |||||
| Current smoker, % | 20.8 | 13.2 | 17.6 | 13.4 | 0.01 |
| Past medical history, % | |||||
| diabetes mellitus | 32.7 | 38.1 | 48.6 | 55.1 | <0.0001 |
| ischemic heart disease | 30.1 | 37.6 | 39.2 | 46.6 | <0.0001 |
| congestive heart failure | 32.7 | 38.5 | 38.6 | 44.1 | 0.0007 |
| peripheral vascular disease | 18.5 | 24.4 | 27.3 | 27.7 | 0.0005 |
| Medication use, % | |||||
| aspirin | 22.3 | 31.2 | 29.8 | 29.9 | 0.009 |
| warfarin | 7.9 | 11.2 | 6.9 | 9.9 | 0.6 |
| angiotensin converting enzyme inhibitor | 22.7 | 28.3 | 24.1 | 24.4 | 0.7 |
| calcium channel blocker | 50.5 | 53.2 | 47.3 | 49.6 | 0.6 |
| erythropoietin | 89.4 | 89.3 | 90.6 | 91.5 | 0.3 |
| Years on dialysis, median (IQR) | 2.4 (1.0 to 4.7) | 2.2 (1.1 to 5.4) | 1.8 (0.8 to 4.3) | 2.2 (1.0 to 4.9) | 0.8 |
| Serum albumin, g/dl, mean (SD) | 3.7 (0.3) | 3.7 (0.4) | 3.6 (0.3) | 3.6 (0.3) | <0.0001 |
| Hematocrit (%) | 33.7 (4.5) | 33.3 (4.6) | 33.7 (4.3) | 33.8 (4.6) | 0.7 |
| Predialysis (mmHg) | |||||
| SBP (SD) | 152 (21) | 152 (22) | 154 (22) | 152 (23) | 0.7 |
| DBP (SD) | 83 (13) | 84 (13) | 82 (12) | 80 (13) | 0.001 |
| Postdialysis (mmHg) | |||||
| SBP (SD) | 141 (22) | 138 (21) | 138 (22) | 132 (19) | <0.0001 |
| DBP (SD) | 77 (13) | 76 (12) | 74 (12) | 71 (10) | <0.0001 |
| Dialysis session minimum (mmHg) | |||||
| SBP (SD) | 126 (18) | 122 (18) | 119 (17) | 108 (16) | <0.0001 |
| DBP (SD) | 72 (11) | 71 (11) | 67 (10) | 61 (11) | <0.0001 |
aCalculated using two-sided Cochran–Armitage trend test or linear regression as appropriate.