Table 5.
Haplotype analysis for C3 SNPs using SNPStats
Haplotype | R102G (C>G) | R304 (A>G) | P314L (C>T) | P518 (C>A) | Control Frequency | DDD Frequency | OR (95%CI) | P-value |
---|---|---|---|---|---|---|---|---|
1 | C | G | C | C | 0.6417 | 0.5004 | 1.00 | — |
2 | G | G | T | A | 0.1354 | 0.2389 | 2.12 (1.24 to 3.60) | 0.0061 |
3 | C | A | C | C | 0.1305 | 0.1095 | 1.13 (0.63 to 2.03) | 0.54 |
4 | C | G | T | A | 0.0218 | 0.0565 | — | NS |
The reference haplotype, which is the most common haplotype in both groups, has OR = 1; the risk haplotype is in bold type. P-values < 0.05 are significant.