Table 2.
Calciotropic hormones and biochemical markers of bone turnover among patients with and without fracture
| Fracture | Nonfracture | Percent Difference between Means | Univariate Logistic Regression OR (95% CI) for each SD increase in BTM | Unadjusted P | Age-, Gender-, and Diabetes-Adjusted P | Normal Range for Premenopausal Women | |
|---|---|---|---|---|---|---|---|
| iPTH, pg/ml | 105 (40 to 249) | 68 (39 to 138) | 42 | 1.24 (0.77 to 2.00) | NS | NS | 14 to 66 |
| 25OHD, ng/ml | 29 (20 to 37) | 32 (22 to 38) | −4 | 0.96 (0.56 to 1.63) | NS | NS | >30 |
| FGF-23, RU/ml | 175 (115 to 578) | 162 (107 to 303) | 44 | 1.67 (0.74 to 3.84) | NS | NS | <100 |
| BSAP, U/L | 30.3 (24.9 to 45.4) | 29.6 (20.8 to 40.7) | 8 | 1.21 (0.72 to 2.05) | NS | 0.059 | 11.6 to 29.6 |
| Osteocalcin, ng/ml | 41.8 (24.1 to 66.0) | 24.2 (14.2 to 41.6) | 52 | 2.66 (1.27 to 5.54) | 0.006 | 0.003 | 8.4 to 33.9 |
| P1NP, μl/L | 79.5 (58.0 to 92.0) | 54.0 (39.0 to 79.0) | 42 | 3.25 (1.50 to 7.05) | 0.0008 | 0.0007 | 19 to 83 |
| CTX, ng/ml | 1.24 (0.77 to 1.47) | 0.87 (0.52 to 1.35) | 19 | 1.78 (0.94 to 3.38) | 0.047 | 0.03 | 0.11 to 0.74 |
| Trap-5b, U/L | 5.33 (4.01 to 7.47) | 4.41 (3.38 to 5.36) | 29 | 2.31 (1.21 to 4.42) | 0.01 | 0.006 | 1.03 to 4.15 |
Values presented as median (IQR).