Table 5.
Diagnostic test characteristics for fracture: BTM levels in the upper two tertiles and a FN T-score of −2 or less versus other BTM and FN T-score groups
Sensitivity (95% CI) | Specificity (95% CI) | PPV (95% CI) | NPV (95% CI) | Positive Likelihood Ratio (95% CI) | Negative Likelihood Ratio (95% CI) | |
---|---|---|---|---|---|---|
Osteocalcin ≥ 21 and FN T-score of −2 or less | 56 (37 to 79) | 81 (69 to 90) | 54 (33 to 74) | 84 (72 to 92) | 3.17 (1.68 to 5.99) | 0.50 (0.69 to 0.84) |
P1NP ≥ 46 and FN T-score of −2 or less | 63 (41 to 82) | 86 (74 to 93) | 64 (41 to 82) | 86 (74 to 93) | 4.61 (2.25 to 9.45) | 0.42 (0.24 to 0.74) |
Trap-5b ≥ 3.7 and FN T-score −2 or less | 59 (37 to 79) | 81 (68 to 90) | 54 (33 to 74) | 84 (71 to 92) | 3.12 (1.65 to 5.88) | 0.50 (0.30 to 0.84) |
PPV, positive predictive value; NPV, negative predictive value.