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. 2011 Aug;22(8):1560–1572. doi: 10.1681/ASN.2010121275

Table 5.

Diagnostic test characteristics for fracture: BTM levels in the upper two tertiles and a FN T-score of −2 or less versus other BTM and FN T-score groups

Sensitivity (95% CI) Specificity (95% CI) PPV (95% CI) NPV (95% CI) Positive Likelihood Ratio (95% CI) Negative Likelihood Ratio (95% CI)
Osteocalcin ≥ 21 and FN T-score of −2 or less 56 (37 to 79) 81 (69 to 90) 54 (33 to 74) 84 (72 to 92) 3.17 (1.68 to 5.99) 0.50 (0.69 to 0.84)
P1NP ≥ 46 and FN T-score of −2 or less 63 (41 to 82) 86 (74 to 93) 64 (41 to 82) 86 (74 to 93) 4.61 (2.25 to 9.45) 0.42 (0.24 to 0.74)
Trap-5b ≥ 3.7 and FN T-score −2 or less 59 (37 to 79) 81 (68 to 90) 54 (33 to 74) 84 (71 to 92) 3.12 (1.65 to 5.88) 0.50 (0.30 to 0.84)

PPV, positive predictive value; NPV, negative predictive value.