Table 2.
Functional magnetic resonance brain imaging studies comparing maltreated to non-maltreated individuals.
Studies | ED | Mean age years | Sample | Task | Summary of results |
---|---|---|---|---|---|
Maheu et al. (2010) | Yes | 13.6 | 11 M vs. 19 NM | FP | M > NM, left amygdala in response to fearful and angry faces, right amygdala: n.s. |
Tottenham et al. (2011) | Yes | 10.1 | 22 M vs.22 NM | FP | M > NM, in left and right amygdala in response to fearful faces |
Carrion et al. (2008) | No | 13.5 | 16 MP vs.16 NM | GNG | M > NM, in left and right ACC when in contrast no-go minus go trials |
Mueller et al. (2010) | Yes | 13.0 | 12 M vs. 21 NM | STOP | M > NM, in left and right ACC when contrast correct change minus correct go |
Carrion et al. (2010) | No | 13.9 | 16 MP vs. 11 NM | VDM | M < NM, right HIPP activity negatively correlated with symptoms severity, left HIPP: n.s. |
Grant et al. (2011) | No | 32.8 | 10 MD vs. 10 M vs. 16 NM | FTF | M > MD = NM, in right amygdala response to sad faces, left amygdala: n.s. |
Dillon et al. (2009) | No | 30.8 | 13 M vs. 21 NM | R/L-P | M < NM, blunted brain response to reward cues in the left pallidus |
Croy et al. (2010) | No | 39.9 | 12 M vs. 10 NM | OS | M > NM, increased activation in posterior cingulate cortex and decreased activation in subgenual ACC |
ACC, anterior cingulate cortex; ED, early deprivation; FP, face processing; FTF, Flanker task with face stimuli; GNG = Go/No-go; M, maltreated; MD, maltreated with depression; MP, maltreated with PTSD/PTSD symptomatology; NM, non-maltreated; R/L-P, reward/loss processing; STOP, stop task; VDM, verbal declarative memory.