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Effects of I/R on RhoA activation and PKD phosphorylation. (A) Representative blots showing time course of RhoA activation and PKD phosphorylation in response to I/R in the isolated perfused WT mouse hearts. (B) Quantification of change in RhoA activation and PKD phosphorylation by 30-minute ischemia followed by 30-minute reperfusion. *P < 0.05 versus preischemic control (n = 3 to 4). Data are shown as mean ± SEM.
