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. 2011 Jul 1;121(8):3206–3219. doi: 10.1172/JCI45273

Figure 6. BMP2 increases the percentage of ALDH+ and ALDH+CD133+ CSCs.

Figure 6

(A) FACS analysis of SKOV3 cells cultured with either PBS (No Tx Control) or BMP2 (100 ng/ml) for 72 hours. FACS analysis of SKOV3 cells cultured in a 1:1 ratio with either adipose control MSCs or CA-MSCs in the absence or presence of Noggin. DEAB control is shown. Numbers represent the percentage of Aldefluor+ cells. (B) Results of FACS analysis of primary tumor spheres from 3 different patients treated with PBS (control) or BMP2 (100 ng/ml) for 7 days. The percentage of ALDH+ cells and ALDH+CD133+ cells for each patient sample is shown.