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. 2011 Jul 1;121(8):3258–3268. doi: 10.1172/JCI46267

Figure 4. Mitochondrial dysfunction in dKO muscle.

Figure 4

(A) Mitochondria were isolated from red and white gastrocnemius muscle, and oxygen consumption rate (OCR) was measured for RCR, ADP-stimulated state 3 respiration (ADP), and FCCP-stimulated respiration (FCCP). n = 6 (WT and dKO). *P < 0.05 vs. WT. (B) Fatty acid oxidation was measured in isolated mitochondria from red and white gastrocnemius muscle. Citrate synthase enzyme activity was measured in isolated mitochondria from red and white quadriceps muscle. n = 6 (WT and dKO). *P < 0.05 vs. WT.