Table 2.
Measured and Reported Somatic Life Spans
| Study | wt Life Span (d) | Mutation/Condition | Mutant Life Span | %Change |
| Present study* | 17, 17.5 | BD(D5 Adults) | 19, 25 | +12, +43 |
| Lee and colleagues (37) † | 14.6 | BD(D4 Adults) | 19.4 | +24.5 |
| Kaberlein and colleagues (38) | 19 | BD(D2 Adults) | 30 | +50 |
| Friedman and Johnson (8) | 15 | age-1(hx546) | 25.5 | +65 |
| Kenyon and colleagues (39) | 20 | daf-2(e1370) | 42 | +110 |
| Lakowski and Hekimi (36) | 19.5 | eat-2(ad465) | 25.1 | +29 |
| Feng and colleagues (40) | 20.3 | isp-1(qm150) | 33 | +65 |
| Van Gilst and colleagues (41) | 17 | nhr-49(nr2041) | 7 | −59 |
| Wilson and colleagues (42) † | 12.7 | skn-1(zu67) | 9.9 | −28 |
| Lin and colleagues (43) ‡ | 20 | daf-16(mu86) | 16 | −20 |
| Panowski and colleagues (24) ‡ | 22 | pha-4(zu225) | 20 | −9.8 |
| Hajdu-Cronin and colleagues (44) | 19 | hsf-1(sy441) | 12.4 | −35 |
| Arantes-Olivera and colleagues (45) | 19.4 | fog-2(q71) | 20.7(not significant) | +6.7 |
| Park and colleagues (46) | 18.6 | nlp-7(tm2984) | 16.2 | −14.8 |
| Park and colleagues (46) | 18.6 | cup-4(ok837) | 17.4 | −6.9 |
Notes: AL = ad libitum; AVG = average; BD = bacterially deprived; wt = wild type.
*
Median life spans reported for two different cohorts of unmated animals randomly selected from the raw data. The “(D5 Adults)” designates that bacterial deprivation was initiated at Day 5 of adulthood. Subsequent notations follow the same pattern.
†
These studies used the fem-1(hc17) background as a surrogate for wild type.
‡
There were no numbers in the text of these manuscripts except percent difference; data extrapolated from figures.