Figure 1.
The expression profiles of CAMK2B in the PFC of normal developing individuals and suicide victims. (A) The scatter plot with a locally weighted scatter plot smoothing (LOWESS) line demonstrates gradual decreases in expression levels of CAMK2B in the PFC of normal humans ranging in age from birth to 49 years. Points are colored by the predefined age groups: red = neonate, green = infant, blue = toddler, light blue = school age, pink = teenage, yellow = young adult, gray: adult. (B) The plot with fold changes and 95% confidence intervals shows consistent up-regulation of CAMK2B in the PFC of suicide victims as compared to the non-suicide controls across nine microarray studies. A combined analysis shown on the bottom represents the weighted fold change and 95% confidence intervals. Individual microarray probes for CAMK2B across multiple studies are shown on the left (Study ID and Affymetrix probe ID). Red circle: adjusted p < 0.05, Cyan circle: adjusted p > 0.05.