(A) Tissue slides were stained with antibodies for CD11b (red), and CD15 (green), and shows dual positive cells (yellow), indicative of MDSC. (B) Intracellular Foxp3 staining as a marker of Treg (green). No immune infiltrate was detectable in normal human pancreas tissue (data not shown).
MDSC: Myeloid-derived suppressor cell.
Images courtesy of David C Linehan and Jonathan B Mitchem, Washington University, Department of Surgery.