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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Immunotherapy. 2011 Apr;3(4):517–537. doi: 10.2217/imt.11.10

Figure 4. Depiction of ideal therapy strategy.

Figure 4

Prior to therapy, the immunological milieu is characterized by high levels of immune suppression and low levels of immune responders, as well as immunological memory. The ideal immune therapy not only augments the antigen-specific immune response, but also reduces immune suppression. Key players such as NK cells, macrophages, B cells, complement and cytokines have been omitted to increase clarity.

ADCC: Antibody-dependent cell cytotoxicity;

MDSC: Myeloid-derived suppressor cell; PC: Pancreatic cancer.