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. 2011 Feb 3;140(2):433–440. doi: 10.1378/chest.10-2885

Table 3.

—Adjusted Association Between the Number of Positive LNs and Survival

Variable Lung Cancer-Specific Survival Hazard Ratio (95% CI) Overall Survival Hazard Ratio (95% CI)
No. of positive LNs
 1 Reference Reference
 2-3 1.16 (1.03-1.30) 1.13 (1.03-1.26)
 4-8 1.53 (1.34-1.75) 1.46 (1.30-1.64)
 > 8 2.25 (1.80-2.81) 2.17 (1.78-2.65)
Age, y 1.03 (1.02-1.04) 1.03 (1.03-1.04)
Female gender 0.79 (0.71-0.88) 0.78 (0.71-0.85)
Race/ethnicity
 White Reference Reference
 Black 0.91 (0.74-1.12) 0.96 (0.81-1.15)
 Hispanic 1.00 (0.77-1.30) 1.08 (0.86-1.35)
 Other 0.95 (0.77-1.17) 0.98 (0.82-1.17)
Married 0.90 (0.81-1.00) 0.87 (0.79-0.95)
Histology
 Adenocarcinoma Reference Reference
 Squamous cell carcinoma 0.66 (0.59-0.75) 0.76 (0.69-0.84)
 Large cell carcinoma 1.01 (0.83-1.24) 1.12 (0.94-1.33)
 Bronchioalveolar carcinoma 0.91 (0.73-1.13) 0.97 (0.80-1.18)
 Other 0.75 (0.59-0.96) 0.82 (0.67-1.01)
Tumor status
 T1A Reference Reference
 T1B 1.42 (1.12-1.80) 1.43 (1.17-1.75)
 T2 1.29 (1.00-1.65) 1.30 (1.05-1.61)
 T2A 1.48 (1.20-1.83) 1.46 (1.22-1.75)
 T2B 1.94 (1.54-2.45) 1.79 (1.47-2.19)
 T3 2.21 (1.76-2.77) 1.97 (1.62-2.40)
Tumor location
 Upper lobe Reference Reference
 Middle lobe 1.24 (0.94-1.64) 1.21 (0.96-1.54)
 Lower lobe 1.17 (1.05-1.30) 1.12 (1.02-1.23)
 Other location 1.20 (1.01-1.43) 1.22 (1.05-1.42)
Type of surgery
 Lobectomy Reference Reference
 Pneumonectomy 1.12 (1.00-1.26) 1.11 (1.01-1.23)
Postoperative radiation therapy 1.11 (0.99-1.23) 1.11 (1.01-1.22)

See Table 1 legend for expansion of abbreviation.