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. Author manuscript; available in PMC: 2011 Aug 2.
Published in final edited form as: Am J Kidney Dis. 2010 Sep 16;56(6):1168–1174. doi: 10.1053/j.ajkd.2010.06.006

Table 1.

Etiologies of Thrombotic Microangiopathy

E Coli O157:H7 or other shiga toxin producing organisms
ADAMTS13 deficiency
Complement regulatory protein deficiencies or mutations
Drugs (Calcineurin inhibitors, oral contraceptives, chemotherapeutic agents, ticlodopine, clopidogrel, quinine)
Pregnancy related
Neuraminidase producing organisms leading to T antigen recognition and possible endothelial cell injury
Hemodynamic factors including malignant hypertension
Idiopathic