Table 1.
Etiologies of Thrombotic Microangiopathy
| E Coli O157:H7 or other shiga toxin producing organisms |
| ADAMTS13 deficiency |
| Complement regulatory protein deficiencies or mutations |
| Drugs (Calcineurin inhibitors, oral contraceptives, chemotherapeutic agents, ticlodopine, clopidogrel, quinine) |
| Pregnancy related |
| Neuraminidase producing organisms leading to T antigen recognition and possible endothelial cell injury |
| Hemodynamic factors including malignant hypertension |
| Idiopathic |