Table 5. Relative Risks (RR)* of Prostate Cancer Associated with AMACR Genotypes Stratified by Red Meat Consumption in Caucasian Men ˆ.
| Tertile of Red Meat Intake | ||||
|---|---|---|---|---|
| SNP | Genotype | 1st RR (95% CI) | 2nd RR (95% CI) | 3rd RR (95% CI) |
| rs34680 | ||||
| CC | 1.00 (Referent) | 1.00 (Referent) | 1.00 (Referent) | |
| CT + TT | 0.86 (0.59 – 1.24) | 1.35 (0.94 – 1.93) | 0.87 (061 – 1.23) | |
| rs34688 | ||||
| CC | 1.00 (Referent) | 1.00 (Referent) | 1.00 (Referent) | |
| CT + TT | 0.80 (0.56 – 1.12) | 1.25 (0.90 – 1.74) | 0.97 (0.70 – 1.34) | |
| rs250412 | ||||
| GG | 1.00 (Referent) | 1.00 (Referent) | 1.00 (Referent) | |
| GA + AA | 0.99 (0.72 – 1.37) | 0.94 (0.68 – 1.29) | 0.94 (0.69 – 1.28) | |
| rs2278008 | ||||
| TT | 1.00 (Referent) | 1.00 (Referent) | 1.00 (Referent) | |
| TC + CC | 0.97 (0.70 – 1.33) | 0.78 (0.57 – 1.07) | 0.99 (0.73 – 1.34) | |
| rs2287939 | ||||
| CC | 1.00 (Referent) | 1.00 (Referent) | 1.00 (Referent) | |
| CT + TT | 0.99 (0.73 – 1.36) | 0.81 (0.60 – 1.10) | 0.91 (0.67 – 1.23) | |
| rs2652130 | ||||
| AA | 1.00 (Referent) | 1.00 (Referent) | 1.00 (Referent) | |
| AC + CC | 0.75 (0.51 – 1.12) | 1.22 (0.85 – 1.75) | 0.83 (0.57 – 1.18) | |
| rs3195676 | ||||
| AA | 1.00 (Referent) | 1.00 (Referent) | 1.00 (Referent) | |
| AG + GG | 0.83 (0.59 – 1.17) | 0.86 (0.61 – 1.19) | 0.78 (0.56 – 1.10) | |
| rs6863657 | ||||
| GG | 1.00 (Referent) | 1.00 (Referent) | 1.00 (Referent) | |
| GA + AA | 1.01 (0.67 – 1.51) | 1.02 (0.69 – 1.50) | 1.14 (0.77 – 1.68) | |
| rs7721230 | ||||
| AA | 1.00 (Referent) | 1.00 (Referent) | 1.00 (Referent) | |
| AG + GG | 0.89 (0.65 – 1.23) | 0.91 (0.66 – 1.25) | 0.80 (0.59 – 1.10) | |
| rs10941112 | ||||
| AA | 1.00 (Referent) | 1.00 (Referent) | 1.00 (Referent) | |
| AG + GG | 0.88 (0.62 – 1.24) | 0.88 (0.63 – 1.23) | 0.80 (0.57 – 1.13) | |
Adjusted for age, family history of prostate cancer, PSA screening, BMI and total caloric intake
There was no evidence for interaction by LR test (all p > 0.1)