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Observed gene expression and double-layered mixture model (DLMM) score against copy number probabilities in ERBB2 and CYCLINE (CCNE1) genes. ERBB2 was selected by DLMM, genomic continuous submatrix (GCSM), and nonparametric tests as top candidate, while CYCLINE was selected only by the nonparametric tests. Other rank-based tests did not pick up CYCLINE either. However, copy number probabilities in CCNE1 is significantly high in only one out of 37 tumor samples.
