Table 1.
Type of Hb | Size | P50 (mm Hg) | N | koff, O2 (s −1) | kon, CO 106 M−1 s−1 | kox, NO 106 M−1 s−1 | References |
---|---|---|---|---|---|---|---|
Hb | |||||||
Human (Hemosol Corp.) | 64 kDa | 14.50 | 2.31 | 42.90 | 0.200 | 18.8 | 47 |
Human (TFF) | 64 kDa | 14.07 | 2.23 | 40.40 | 0.214 | 18.5 | 47 |
Bovine (Biopure Corp.) | 64 kDa | 29.22 | 2.10 | 37.80 | 0.200 | 19.0 | 47 |
Bovine (TFF) | 64 kDa | 28.58 | 2.49 | 36.10 | 0.216 | 18.3 | 47 |
Human (with PLP) | 64 kDa | 23.00 | 1.9 | 84.00 | 0.210 | 87.0 | 28, 46 |
Human (TFF) | 64 kDa | 13.00 | 2.58 | 38.71 | 0.200 | 27.5 | * |
Bovine (TFF) | 64 kDa | 26.02 | 2.75 | 38.97 | 0.198 | 28.2 | * |
Polymerized Hb | |||||||
Bovine (T- and R-state) | 16–26 MDa | 0.66–41 | < 1 | 22–53 | 0.18–4.80 | 17.5–18.9 | 56 |
Bovine (Oxyglobin®) | 200 kDa | 35.10 | 1.40 | 60.00 | 0.150 | 66.0 | 28, 46, 57 |
Human (Hemolink®) | 64–600 kDa | 47.30 | 1.00 | 130 | 0.120 | - | 58 |
RBCs | |||||||
Human and Rat | 8 μm | 25.10 | 2.8 | 4.4 | 0.065 | 0.05 | 31, 49, 55 |
Human (GSABC, D.C.) | 8 μm | 20.00 | 2.18 | 16.67 | 0.130 | 0.03 | * |
Bovine (QUAD 5, MT) | 8 μm | 30.20 | 2.62 | 2.01 | 0.087 | 0.31 | * |
PEG-LEHs | |||||||
Human (with PLP) | 279 nm | 25–31 | 2.1 | 32.00 | 0.210 | 8.80 | 28, 46 |
Human (TFF) | 176 nm | 22.87 | 2.11 | 21.57 | 0.212 | 4.00 | * |
Bovine (TFF) | 174 nm | 19.83 | 1.44 | 13.13 | 0.220 | 2.60 | * |
This study