Table 1.
Variable | All | Low VVC | Optimal VVC | High VVC |
---|---|---|---|---|
n = 47 | n = 21 | n = 16 | n = 10 | |
Age, yrs | 58 ± 2 | 59 ± 3 | 57 ± 3 | 58 ± 5 |
Male, % | 72 | 57 | 88 | 80 |
BMI, kg/m2 | 31 ± 1 | 31 ± 1 | 33 ± 1 | 28 ± 2 |
Hypertension, % | 81 | 90 | 81 | 60 |
SBP, mmHg | 122 ± 2 | 125 ± 3 | 121 ± 5 | 118 ± 6 |
DBP, mmHg | 66 ± 2 | 65 ± 3 | 70 ± 3 | 60 ± 4 |
MAP, mmHg | 85 ± 2 | 85 ± 3 | 86 ± 3 | 79 ± 4 |
PP, mmHg | 56 ± 2 | 59 ± 3 | 51 ± 4 | 57 ± 5 |
HR, bpm | 68 ± 2 | 65 ± 3 | 70 ± 3 | 71 ± 5 |
Diabetes mellitus, % | 34 | 29 | 44 | 30 |
Hyperlipidemia, % | 83 | 81 | 94 | 70 |
Total cholesterol, mg/dl | 167 ± 7 | 165 ± 12 | 179 ± 11 | 154 ± 15 |
LDL cholesterol, mg/dl | 95 ± 6 | 92 ± 8 | 96 ± 12 | 97 ± 15 |
HDL cholesterol, mg/dl | 35 ± 1 | 35 ± 3 | 35 ± 3 | 36 ± 2 |
Triglycerides, mg/dl | 174 ± 24 | 188 ± 42 | 208 ± 45 | 102 ± 13 |
CAD, % | 79 | 86 | 75 | 70 |
Current smoker, % | 23 | 29 | 12 | 30 |
Family history CVD, % | 47 | 57 | 38 | 40 |
Medications, % | ||||
Aspirin | 23 | 29 | 6 | 40 |
Statin | 25 | 33 | 6 | 40 |
Anti-hypertensive agent | 52 | 57 | 44 | 50 |
Ejection Fraction, % | 58 ± 2 | 73 ± 2 | 53 ± 2‡ | 34 ± 2‡ † |
Fractional Shortening, % | 32 ± 2 | 43 ± 2 | 28 ± 1‡ | 16 ± 1‡ † |
Stroke Work Index | 49 ± 3 | 62 ± 3 | 46 ± 3‡ | 26 ± 2‡ † |
Significantly different from optimal (p<0.05).
Significantly different from low (p<0.05).