Figure 1.

Flow of donors and classification of disease (as defined by sTfR-F index) using two cut-offs for hepcidin. A total of 261 donors were recruited into the study. When a hepcidin cut-off of <8 ng/mL was selected, 10.3% were considered iron-deficient, of whom 81.5% were correctly classified; of the 89.7% considered iron replete, 86.8% were correctly classidied. When a hepcidin cut-off of <18 ng/mL was selected, 27.6% of this population were considered iron-deficient, of whom 58.3% were correctly classified; of the 72.4% not considered iron-deficient, 94.2% were correctly classified.