Table 6.
Laboratory parameters at baseline and at final evaluation (on week 50 or at the patient’s last evaluation in case of early withdrawal from the study)
| Laboratory parameters | Evaluation | Mean (SD) | Minimum | Maximum | P value |
|---|---|---|---|---|---|
| Total cholesterol (mg/dL) | Baseline | 172.9 (34.5) | 112 | 279 | 0.758 |
| Final | 171.7 (33.2) | 106 | 233 | ||
| HDL (mg/dL) | Baseline | 45.6 (13.1) | 27 | 78 | 0.044 |
| Final | 43.5 (13.5) | 24 | 76 | ||
| LDL (mg/dL) | Baseline | 99.6 (28.8) | 32 | 184 | |
| Final | 97.0 (29.3) | 24 | 163 | 0.384 | |
| VLDL (mg/dL) | Baseline | 23.1 (11.6) | 9 | 62 | |
| Final | 27.1 (14.4) | 7 | 73 | 0.074 | |
| Creatinine (mg/dL) | Baseline | 0.86 (0.17) | 0.40 | 1.10 | |
| Final | 0.96 (0.18) | 0.56 | 1.28 | 0.005 | |
| Fasting glycemia (mg/dL) | Baseline | 92.1 (25.6) | 75 | 249 | |
| Final | 92.0 (10.9) | 57 | 114 | 0.153 | |
| Prolactin (ng/mL) | Baseline | 36.2 (40.1) | 2.1 | 181.0 | |
| Final | 49.9 (43.6) | 4.1 | 232.4 | 0.006 | |
| Triglycerides (mg/dL) | Baseline | 112.5 (62.0) | 42.0 | 313.0 | |
| Final | 123.8 (71.7) | 36.0 | 367.0 | 0.201 |
Abbreviations: SD, standard deviation; HDL, high-density lipoprotein LDL, low-density lipoprotein; VLDL, very low-density lipoprotein.