Figure 4. OVA-containing tumor exosomes were not effective in suppressing KLH-specific DTH response.

Mice pre-sensitized with KLH were treated with 10 µg of exosomes or PBS in their right hind paws and were challenged with KLH antigen at both hind paws. Paw swellings were measured 24 h and 48 h later. The increases in footpad thickness (×0.01 mm) of one representative experiment (n = 5) (A) and the normalized fold increases in footpad thickness of two independent experiments (n = 10) (B) are shown. NS: not significant.