Figure 10. Model for gliogenesis in the retina.
As the last progenitors exit the cell cycle (red), a subset of the postmitotic progeny are committed to the glial fate. These presumptive Müller glia (yellow) retain Notch signaling and are prevented from differentiating into bipolar neurons or rod photoreceptors; however, their glial identity is labile, and it is only with the increase in the gliogenic signals over the next week that secondary mechanisms stabilize the glial fate (green).