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Inhibition of HUVEC proliferation by P11. A, HUVECs were incubated with different concentrations (0.1, 1, 10, and 100 μg/ml) of P11 for 72 h. The adherent cells were then trypsinized and counted. B, and C, NIH 3T3 cells and U87 glioma cells were incubated with different concentrations (0.1, 1, 10, and 100 μg/ml) of P11, RGD peptide (500 μg/ml) or RGE peptide (500 μg/ml) for 48 h. The adherent cells were then trypsinized and counted.
