Table 1.
Selected examples of iPRECIO® applications in Japan with details of species, agent/drug, administration site, and infusion protocol.
| Customer | Animal | Drug | Administration route | Mode | Flow-rate (μl/h) |
|---|---|---|---|---|---|
| Pharmaceutical Company | Rat | The toxicity test of a circulation related medicine | External jugular vein | Confidential | Confidential |
| Pharmaceutical Company | Rat | Reproductive hormone | External jugular vein | RCV/constant | 5–10 |
| Pharmaceutical Company | Rat | Diabetes related medicine | External jugular vein | RCV/variable | 3–15 |
| Pharmaceutical Company | Rat | Epilepsy related medicine | Injection in the skull | RCV/constant | 1–10 |
| Pharmaceutical Company | Rat | Antiphlogistic–sedative–drug relation | Subcutaneous | RCV/Constant | 1–20 |
| Pharmaceutical Company | Rat | Ophthalmology region medicine | Fundus oculi | RCV/constant | 3–15 |
| Pharmaceutical Company | Rat | Metabolism related | External jugular vein | RCV/constant | 5–10 |
| Pharmaceutical Company | Rat | pH5 strong acidity solution | Subcutaneous | Confidential | Confidential |
| Fukuyama University | Rat | Pain | Subcutaneous | Confidential | Confidential |
| Gifu university | Rat | Angiotensin 2 losartan | External jugular vein | Instant/variable | 3–30 |
| Hoshi University | Hamster | Confidential | External jugular vein and Subcutaneous | RCV/constant | 1–15 |
| Hoshi University | Rat | Confidential | External jugular vein | RCV/constant | 5–30 |
| Hoshi University | Rat | Pain clinic related | Hypodermoclysis | RCV/constant | 1–30 |
| Jichi Medical University | Mouse | Confidential | Subcutaneous | Confidential | Confidential |
| Nagoya City University | Rat | Angiotensin II | External jugular vein | Confidential | Confidential |
| National Institute of Agro biological Sciences | Goat | Confidential | Vein | RCV/constant | 5–30 |
| National Center of Neurology and Psychiatry (NCNP) | Mouse | Confidential | Subcutaneous | RCV/constant | 1–15 |
| Nihon University | Rat | Confidential | External jugular vein | RCV/constant | 3–10 |
| Osaka City University | Rat | Neurotransmitter | Injection in the skull | RCV/constant | 1–15 |
| Osaka University of Pharmaceutical Sciences | Rat | Vitamin B12 | External jugular vein | Confidential | Confidential |
| Shiga University of Medical Science | Confidential | Reproduction related | Subcutaneous | Instant/variable | 1–7 |
| Shiga University of Medical Science | Rat | Reproductive hormone | External jugular vein | RCV/constant | 5–10 |
| Tokyo Women’s Medical University (TWMU) | Hamster | Confidential | External jugular vein and Subcutaneous | RCV/constant | 1–15 |
| The University of Tokyo | Rat | Nicotine | External jugular vein | Confidential | Confidential |
| The University of Tokyo | Rat | Confidential | External jugular vein | RCV/constant | 5–15 |
RCV Mode is a function of iPRECIO® pumps which allow saline to be infused initially during the recovery period prior to agent administration. At the appropriate time, saline is replaced with agent to allow the programmed start time taking into account dead volumes within the infusion system.