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. 2011 Apr 5;19(8):1558–1568. doi: 10.1038/mt.2011.29

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Copyright © 2011 The American Society of Gene & Cell Therapy

This work is licensed under the Creative Commons Attribution-NonCommercial-No Derivative Works 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/

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CD4⁺CD25⁺ T-cells in draining lymph nodes (DLNs) from mice treated with Ad-ΔB7/IL12/GMCSF and/or dendritic cells (DCs). DLNs were collected from mice treated with phosphate-buffered saline (PBS), DC, Ad-ΔB7/IL12/GMCSF, Ad-ΔB7/IL12/GMCSF plus DCs, or Ad-ΔB7/IL12/GMCSF (H; high-dose of Ad) plus DCs. Proportion of CD4⁺CD25⁺ T-cells in the DLNs from different groups of mice were measured by fluorescence-activated cell sorting analysis. Data points represent the mean ± SE of three mice per group, and similar results were obtained from at least two separate experiments. *P < 0.05; **P < 0.01. GM-CSF, granulocyte-macrophage colony-stimulating factor; IL, interleukin.