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. 2011 Jun 21;19(8):1449–1456. doi: 10.1038/mt.2011.99

Figure 2.

Figure 2

Construction of the dual function (DF)-MITO-Porter. (a) Schematic diagram of the preparation of the DF-MITO-Porter. D-SNP, di-lammelar structured nano particle; SUV, small unilamellar vesicles; T-SNP, tetra-lamellar structured nano particle. (b) Diameter and (c) ζ-potential of nano particles of DNase I complexed with stearyl octaarginine (STR-R8) at various molar ratios. Data are represented by the mean ± SD (n = 3–7). C/P, complex-inducer (STR-R8)/protein (DNase I). (d) Characteristics of the DF-MITO-Porter containing DNase I. Diameter, polydispersity index (PDI) and ζ-potential of carriers were measured. Data are represented by the mean ± SD (n = 3–4). CHEMS, cholesteryl hemisuccinate (5-cholesten-3-ol 3-hemisuccinate); DOPE, 1,2-dioleoyl-sn-glycero-3-phosphatidyl ethanolamine; PA, phosphatidic acid; SM, sphingomyelin.