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Comparison of global EphA2 C0 dephosphorylation catalyzed by HCPTP-A and HCPTP-B. Aliquots drawn at various time points were resolved on 12% SDS PAGE and either stained with Coomassie blue or probed with an anti-phosphotyrosine antibody (pY20). (A) Dephosphorylation of EphA2 C0 by HCPTP-A. (B) Dephosphorylation of EphA2 C0 by HCPTP-B. The increase in mobility of EphA2 C0 upon dephosphorylation is indicated by arrows.
