Table I.

Levels of testosterone and E2 were measured in serum from Helicobacter pylori-infected INS-GAS mice that were intact, castrated or treated with E2 supplementation

Group	Serum testosterone level (pg/ml)	Serum E2 level (pg/ml)
Intact mice (n = 5)	177.2 ± 36.0	15.5 ± 2.3
Castrated mice (n = 5)	8.7 ± 0.9*	11.6 ± 1.6
E2-treated mice (n = 5)	15.7 ± 4.2*	72.5 ± 19.7**

Castration and E2 significantly reduced testosterone (*P < 0.01) compared with intact mice and E2 supplementation resulted in supraphsyiological levels (**P < 0.05). Values represent the mean ± standard error.