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Crystal structure of bovine galectin-1/Gal(β1-4)GlcNAc complex. (A) Representation of the galectin-1 homodimer bound to Gal(β1-4)GlcNAc (PDB ID 1SLT). (B) Galectin-1 binding site representation. (Sticks) Residues of the CRD and disaccharide. (Dashed lines) H-bonds. One water molecule, conserved in the binding site, participates in a bridged interaction between the protein and the ligand.
