TABLE 1.

Kinetic parameters of spontaneous Tau fibrillation

Kinetic traces of Tau fibrillation are shown in Fig. 1 (B and C) and fitted to the sigmoidal function (see Equation 1). Errors are estimated by three independent experiments.

Tau isoform	Ffinal	t½	k
		min	min−1
1N3RCA	(2.23 ± 0.12) × 103	(7.39 ± 0.92) × 102	(8.24 ± 0.44) × 10−3
1N3RS-S	(3.61 ± 0.14) × 103	(1.17 ± 0.03) × 102	(1.25 ± 0.09) × 10−2
1N4RCA	(5.19 ± 1.13) × 102	(6.55 ± 0.29) × 102	(1.15 ± 0.06) × 10−2
1N4RS-S	(4.07 ± 0.31) × 102	(3.89 ± 0.76) × 102	(8.14 ± 0.50) × 10−3