Figure 1.
(A; 1) pH-dependent G-V shifts in WT BK channels in nominal 0 Ca2+; (2) pH-dependent G-V shifts in WT BK channels in 200 µM Ca2+; (B; 1) pH-dependent G-V shifts in M314 (WT):H365R:H394R channels in nominal 0 Ca2+; (2) pH-dependent G-V shifts in M314 (WT):H365R:H394R channels in 200 µM Ca2+; (C; 1)comparison of WT τapp–V relations between different pH in 0 Ca2+; (2) comparison of WT τapp–V relations between different pH in 200 µM Ca2+; (D; 1) pH-dependent G-V shifts in M314H BK channels in nominal 0 Ca2+; (2) pH-dependent G-V shifts in M314H BK channels in 200 µM Ca2+; (E; 1) pH-dependent G-V shifts in M314H:H365R:H394R channels in nominal 0 Ca2+; (2) pH-dependent G-V shifts in M314H:H365R:H394R channels in 200 µM Ca2+; (F; 1) comparison of M314H τapp–V relations between different pH in 0 Ca2+; (2) comparison of M314H τapp–V relations between different pH in 200 µM Ca2+. (See Tables I and II for fitting parameters.) Each point was calculated from a dataset with n ≥ 3.