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. 2011 Aug;138(2):271–277. doi: 10.1085/jgp.201110661

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© 2011 O’Connell et al.

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Figure 3. — Amikacin/ciprofloxacin supplementation prevents black foci formation. Bright-field micrographs of extracted oocytes incubated for 4 d in tetracycline/gentamicin-supplemented (ND96-GT; A) or amikacin/ciprofloxacin-supplemented media (ND96-ACT; B). Bars, 0.5 mm. Histopathology slices of a compromised oocyte (C) and a healthy oocyte (D), magnified in E and F, respectively. Brackets denote areas of increased pigmentation; arrows indicate areas devoid of pigment molecules, both of which were only observed in infected oocytes.