Figure 5.
(A) The proportion of q-cliques and bicliques for positive and negative interactions. Nine percent of negative biclusters are q-cliques, while 18% of positive biclusters are q-cliques. (B) The left bar plot shows the mean of the mean coexpression of array genes within positive q-cliques, positive bicliques, negative q-cliques, and negative bicliques. The dashed line is the mean MEFIT score between all gene pairs. The right plot shows the mean of the mean number of physical interactions among the array genes of the positive q-cliques, positive bicliques, negative q-cliques, and negative bicliques. The dashed line is the background rate of PPIs between gene pairs. (C) The ratio of q-cliques to q-cliques + bicliques for different types of query alleles. Deletion mutants appear in a high proportion of positive q-cliques, while TS mutants appear in more negative q-cliques. All error bars are bootstrapped 95% confidence intervals.
