Table 2.
Table of the functional analysis made in KEGG for protein signature
| KEGG pathway | KEGG category | n. | P |
|---|---|---|---|
| Cytokine-cytokine receptor interaction | 14 | 9.69e-26 | |
| Cell adhesion molecules (CAMs) | Signaling Molecules and Interaction | 1 | 7.59e-2 |
| Neuroactive ligand-receptor interaction | 1 | 1.67e-1 | |
| Hematopoietic cell lineage | 7 | 6.00e-14 | |
| Natural killer cell mediated cytotoxicity | 4 | 9.12e-7 | |
| Toll-like receptor signaling pathway | Immune System | 3 | 2.19e-5 |
| Fc epsilon RI signaling pathway | 2 | 1.01e-3 | |
| Leukocyte transendothelial migration | 2 | 2.29e-3 | |
| T cell receptor signaling pathway | 1 | 5.57e-2 | |
| Apoptosis | Cell Growth and Death | 5 | 1.54e-9 |
| MAPK signaling pathway | 4 | 2.21e-5 | |
| Jak-STAT signaling pathway | Signal Transduction | 4 | 1.90e-6 |
| TGF-beta signaling pathway | 1 | 4.96e-2 | |
| Adipocytokine signaling pathway | Endocrine System | 3 | 1.13e-5 |
| PPAR signaling pathway | 1 | 4.17e-2 | |
| Epithelial cell signaling in Helicobacter pylori infection | Infectious Diseases | 2 | 8.05e-4 |
| Gap junction | Cell Communication | 2 | 1.33e-3 |
| Focal adhesion | 2 | 6.43e-3 | |
| Glioma | Cancers | 2 | 6.66e-4 |
| Pancreatic cancer | 1 | 4.42e-2 | |
| Type I diabetes mellitus | Metabolic Diseases | 2 | 2.96e-4 |
| Type II diabetes mellitus | 2 | 3.26e-4 | |
| Regulation of actin cytoskeleton | Cell Motility | 2 | 6.89e-3 |
Enriched pathways of the protein signature resulting from the WebGestalt functional analysis with KEGG. For each pathway, the table reports the pathway name, its KEGG category, the number of selected genes (n.) and the p-value. The enriched pathways are displayed in boldface.