Table 3. Relationships between the SLC6A3 variations and regional DAT measures.
Variant | ROI | df | F | p |
3′UTR | Caudate | 5,81 | 5.9 | <0.001* |
Putamen | 5,81 | 2.1 | NS | |
Ventral Str | 5,77 | 3.0 | 0.03* | |
Intron8 | Caudate | 5,89 | 6.2 | <.001* |
Putamen | 5,89 | 2.4 | 0.02* | |
Ventral Str | 5,81 | 2.5 | 0.04* | |
Haplotype | Caudate | 5.85 | 2.6 | <0.01* |
Putamen | 5.85 | 1.7 | NS | |
Ventral Str | 5,81 | 2.6 | 0.03* |
Abbreviations: ROI – region of interest; Ventral Str. – ventral striatum.
Significance level for overall effect of the genotypes (three-genotypes classification) and haplotypes (four haplotypes classification) was set at p<0.05 (ANCOVA); values<0.05 are marked with*.