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. 2011 Aug 3;6(8):e23383. doi: 10.1371/journal.pone.0023383

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Tan et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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BMI1, GLI1, and GLI2 were up-regulated in holoclones, while expression of GLI3 showed no significant change among distinct types of colonies (A). The microRNAs were clustered into two groups, which were elevated (B) and repressed (C) in holoclones respectively. All expression values in distinct types of colonies were normalized against those in paraclones (*, p<0.05).