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Effect of NOX2 deletion on post-MI remodelling. Representative M-mode echocardiographic images from NOX2 knockout mice or wild-type littermates (WT) subjected to left coronary ligation or sham ligation surgery. The extent of LV dilatation and reduction in fractional shortening 4 weeks after MI is significantly reduced in the NOX2 knockout group compared to WT. Reproduced with permission from Looi et al. [81]
