Table 2.

Selected key patents protecting anti-TNFα antibodies

Key patent	Assignee	Main claim	Priority
US5654407	Bayer	A composition comprising human monoclonal antibodies that bind specifically to human tumor necrosis factor α.	March 5, 1993
US6090382	Abbott	An isolated human antibody (..) that dissociates from human TNFα with a Kd of 1 × 10−8 M or less (..)	February 9, 1996
US7012135	UCB	An antibody molecule having specificity for human TNF[alpha], comprising the light chain region hTNF40-gL1 (SEQ ID NO:8) and the heavy chain variable region gh3hTNF40.4 (SEQ ID NO:11).	June 6, 2000