Table 2.
Item by item comparison of SLICC Damage Index (SDI), Lupus Damage Index Questionnaire (LDIQ), and Brief Index of Lupus Damage (BILD) in clinic sample of 81 patients.
| BILD vs. SDI | LDIQ vs. SDI** | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Organ System and Item | SDI # (%) |
BILD # (%) |
% agree |
PABAK | LDIQ # (%) |
% agree |
PABAK | |||
| Ocular | ||||||||||
| Any cataract ever | 14 | 17% | 14 | 17% | 93% | 0.85 | 14 | 19% | 97% | 0.95 |
| Retinal change or optic atrophy | 2 | 2% | 6 | 7% | 93% | 0.85 | 10 | 14% | 89% | 0.78 |
| Neuropsychiatric | ||||||||||
| Cognitive impairment or major psychosis | 6 | 7% | 4 | 5% | 88% | 0.75 | 17 | 23% | 77% | 0.54 |
| Seizures requiring therapy 6+ mos. | 7 | 9% | 4 | 5% | 94% | 0.88 | 3 | 4% | 93% | 0.86 |
| Cerebrovasc accident/resection | 4 | 5% | 10 | 12% | 90% | 0.80 | 5 | 7% | 93% | 0.86 |
| Transverse myelitis | 0 | 1 | 1% | 99% | 0.98 | 12 | 16% | 84% | 0.68 | |
| Cranial/peripheral neuropathy | 6 | 7% | (omitted) | 18 | 24% | 73% | 0.46 | |||
| Renal | ||||||||||
| ESRD (dialysis/transplant) | 6 | 7% | 8 | 10% | 95% | 0.90 | 4 | 5% | 96% | 0.92 |
| GFR <50% | 4 | 5% | (omitted) | 32 | 43% | 62% | 0.24 | |||
| Proteinuria >3.5g/24h | 5 | 6% | (omitted) | 40 | 54% | 53% | 0.05 | |||
| Pulmonary | ||||||||||
| Pulm. hypertension | 2 | 2% | 5 | 6% | 96% | 0.93 | 7 | 9% | 93% | 0.86 |
| Pulm. fibrosis | 0 | - | 0 | - | 100% | 1.00 | 5 | 7% | 93% | 0.86 |
| Shrinking lung | 0 | - | (omitted) | 1 | 1% | 99% | 0.97 | |||
| Pleural fibrosis | 1 | 1% | (omitted) | 4 | 5% | 96% | 0.92 | |||
| Pulm. infarction or resection | 1 | 2% | (omitted) | 5 | 7% | 95% | 0.89 | |||
| Cardiovascular | ||||||||||
| Angina or coronary artery bypass | 0 | - | 2 | 2% | 98% | 0.95 | 3 | 4% | 96% | 0.92 |
| Myocardial infarction | 2 | 2% | 1 | 1% | 98% | 0.95 | 1 | 1% | 99% | 0.97 |
| Pericarditis 6+mos, or pericardiectomy | 5 | 9% | 3 | 5% | 93% | 0.86 | 5 | 9% | 96% | 0.93 |
| Cardiomyopathy | 4 | 5% | (omitted) | 3 | 4% | 99% | 0.97 | |||
| Valvular disease | 1 | 1% | (omitted) | 3 | 4% | 95% | 0.89 | |||
| Peripheral vascular | ||||||||||
| Minor tissue loss (pulp space) | 4 | 5% | 14 | 17% | 88% | 0.75 | 4 | 5% | 95% | 0.89 |
| Sig. tissue loss, ever | 0 | - | 2 | 2% | 98% | 0.95 | 3 | 4% | 96% | 0.92 |
| Venous thrombosis with swelling, | 8 | 10% | 10 | 12% | 88% | 0.75 | 5 | 7% | 88% | 0.76 |
| ulceration or venous stasis | ||||||||||
| Claudication, 6+mos | 0 | - | (omitted) | 9 | 12% | 88% | 0.76 | |||
| Gastrointestinal | ||||||||||
| Chronic peritonitis | 0 | - | 2 | 2% | 98% | 0.95 | 0 | - | 100% | 1.00 |
| Stricture or upper GI tract surgery | 0 | - | 1 | 1% | 99% | 0.98 | 6 | 8% | 92% | 0.84 |
| Infarction/resection bowel, spleen liver, gall bladder |
3 | 4% | (omitted) | 5 | 7% | 97% | 0.95 | |||
| Mesenteric insufficiency | 0 | - | (omitted) | (omitted) | ||||||
| Pancreatic insufficiency | 1 | 1% | (omitted) | 1 | 1% | 100% | 1.00 | |||
| Musculoskeletal | ||||||||||
| Deforming or erosive arthritis* | 2 | 2% | 12 | 15% | 84% | 0.68 | 12 | 16% | 81% | 0.61 |
| Osteoporosis w. fracture or vertebral. collapse |
4 | 5% | 6 | 74% | 95% | 0.90 | 4 | 5% | 92% | 0.84 |
| Avascular necrosis | 7 | 9% | 6 | 7% | 96% | 0.93 | 5 | 7% | 95% | 0.89 |
| Osteomyelitis | 0 | - | 0 | - | 100% | 1.00 | 1 | 1% | 99% | 0.97 |
| Muscle atrophy or weakness | 4 | 5% | (omitted) | 1 | 1% | 93% | 0.86 | |||
| Ruptured Tendon | 0 | - | (omitted) | 1 | 1% | 98% | 0.96 | |||
| Skin | ||||||||||
| Extensive scarring/panniculum* | 8 | 10% | 28 | 35% | 75% | 0.51 | 21 | 28% | 77% | 0.54 |
| Skin ulceration (not thrombosis), >6 mos. |
4 | 5% | 8 | 10% | 93% | 0.85 | 8 | 11% | 92% | 0.84 |
| Scarring chronic alopecia | 5 | 6% | (omitted) | 13 | 18% | 80% | 0.59 | |||
| Premature gonadal failure | 1 | 2% | 13 | 16% | 85% | 0.70 | 6 | 8% | 91% | 0.81 |
| Diabetes | 4 | 5% | 7 | 9% | 90% | 0.80 | 6 | 8% | 95% | 0.89 |
| Malignancy | 1 | 2% | 2 | 2% | 99% | 0.98 | 2 | 3% | 99% | 0.97 |
*
These two items were dropped from the final BILD score.
**
Based on 74 patients with LDIQ score.