Table II.
Regression coefficients for log total IgE from longitudinal models over 1, 2, 3 and 5 years, for individual cytokines (Unadjusted) and for Th2 cytokines adjusted for IFN-γ levels (Adjusted), at 3 and 12 months.*
| Total IgE Ages 1, 2, 3, and 5 years |
|||
|---|---|---|---|
| Coef. | P-value | ||
| 3 Month Cytokines | |||
| Unadjusted | |||
| IL-4 | 0.07 | 0.040 | |
| IL-5† | 0.10 | 0.134 | |
| IL-13 | 0.00 | 0.968 | |
| IFN-γ | −0.03 | 0.345 | |
| Adjusted | |||
| IL-4 | 0.11 | 0.005 | |
| IFN-γ | −0.08 | 0.030 | |
| IL-5† | 0.12 | 0.089 | |
| IFN-γ | −0.04 | 0.214 | |
| IL-13 | 0.03 | 0.446 | |
| IFN-γ | −0.05 | 0.191 | |
| 12 Month Cytokines | |||
| Unadjusted | |||
| IL-4 | 0.13 | <0.001 | |
| IL-5 | 0.12 | <0.001 | |
| IL-13 | 0.06 | 0.086 | |
| IFN-γ | −0.02 | 0.500 | |
| Adjusted | |||
| IL-4 | 0.17 | <0.001 | |
| IFN-γ | −0.09 | 0.010 | |
| IL-5 | 0.14 | <0.001 | |
| IFN-γ | −0.06 | 0.054 | |
| IL-13 | 0.09 | 0.016 | |
| IFN-γ | −0.07 | 0.066 | |
Abbreviation: Coef. (Coefficient)
N3 Months = 295–298; N12 Months = 309–316
Dichotomized: Detectable/Undetectable.