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. Author manuscript; available in PMC: 2012 Nov 15.
Published in final edited form as: J Neurosci Methods. 2011 Mar 8;202(2):158–164. doi: 10.1016/j.jneumeth.2011.03.001

Figure 3.

Figure 3

Evoked DA release using Demon Voltammetry. Shown are concentration-time plots (upper), color plots (lower) and cyclic voltammograms (insets) from (A) an in vitro, (B) an in vivo anesthetized, and (C) a freely moving FSCV experiment. Red bars below concentration-time plots indicate the timing of electrical stimulation. Concentration-time plots represent the concentration of DA over time. Color plots depict the voltammetric current (color in the z-axis) plotted against the applied potential (y-axis) and the acquisition time (x-axis; color plots were magnified to better show DA spikes). Cyclic voltammograms depict two current peaks, one at ~ 600 mV (positive deflection) for DA oxidation and one at ~ −200 mV (negative deflection) for reduction of DA-o-quinone. Peak positions identify the substance oxidized as DA.