Cytokine production by alveolar macrophages from asthmatic and normal subjects. A, IL-8 levels in 24-hour conditioned media from BAL alveolar macrophages from asthmatic and normal subjects treated with either HA or LPS (n = 8, *p < 0.05). B–D, IL-8 levels in 24-hour conditioned media from BAL alveolar macrophages from asthmatic treated with HA or LPS in the presence or absence of TLR2 (B), TLR4 (C) or CD44 (D) antibody pretreatment (n = 3, *p < 0.05, **p < 0.01, ***p < 0.001).