Figure 5. Patients that flare at six weeks post vaccination had higher baseline IFN alpha serum activity.
Patients were divided into individuals that had a flare (flare) and age and race matched SLE patients that did not have a flare during the course of the study (no flare). Shown is the serum IFN alpha activity at baseline and two weeks in the patients that had a flare at 6 weeks (panel A, p value determined by unpaired t test) and those with a flare at 12 weeks (panel B, no significance by unpaired t test). Each symbol represents one individual and the mean and standard error of the mean are shown.