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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: Trends Endocrinol Metab. 2011 May 10;22(8):325–332. doi: 10.1016/j.tem.2011.03.007

Figure 2. Opposing functions of STAT5 in preadipocytes and adipocytes.

Figure 2

STAT5 proteins promote adipogenesis and lipid accumulation. Inhibition of STAT5 activation or expression inhibits adipogenesis in vitro and adipose tissue development in vivo. However, in mature adipocytes, there is strong evidence to suggest that STAT5 has anti-lipogenic function.