| Study design |
Study drug |
| Randomized, double-blinded study |
| Frequency of dosing |
| Study duration |
| Oesophageal pH measurement before enrollment |
| Endoscopic evaluation before enrollment |
| Presence of erosive esophagitis |
| Presence of run-in period |
| Frequency of office visits during active treatment |
| Frequency of office visits throughout entire study |
| Study population |
Total number of subjects in |
| Placebo arm |
| Active treatment arm |
| Total number of subjects who |
| Completed placebo arm |
| Completed active treatment arm |
| Mean age |
| Gender distribution |
| Heartburn response |
Reported relief of heartburn |
| Defined relief of heartburn as “complete relief of heartburn” |
| Quality measures (Jadad score) |
Was study described as randomized? |
| Was study described as double-blinded? |
| Were data on withdrawals and dropouts provided? |
| Was the method of randomization described and appropriate? |
| Was the method of blinding described and appropriate? |
