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. Author manuscript; available in PMC: 2012 Aug 15.
Published in final edited form as: J Immunol. 2011 Jul 8;187(4):2015–2022. doi: 10.4049/jimmunol.1100713

Figure 1. FNB anti-CD3 mAb increases the percentage but not the absolute number of CD4+Foxp3+ T cells.

Figure 1

Mice were treated with FNB anti-CD3 mAb (filled squares) or control Ig (empty circles) and peripheral LNs were harvested at the indicated times. Total cell numbers were determined and T cells subsets were analyzed by flow cytometry. Data shown is normalized to the Ig-treated age-matched mice that were harvested on the same day to control for changes in cell number due to age. (A) Normalized percentage of CD4+ cells within lymphocyte gate. (B) Normalized percentage of Foxp3+ cells within the CD4+ gate. (C) Normalized total CD4+ cell number. (D) Normalized total CD4+Foxp3+ cell number. Each data point represents an individual mouse. Data is representative of two independent experiments.