Table 1.

The substitution reaction between isatin and bromoethane

No.	Solvent	Base	Time (h)	Yield (%)
1	DMF	Na2CO3	24	33
2	DMF	K2CO3	12	89
3	DMF	NaOH	12	40
4	DMF	KOH	12	41
5	DMF	TEA	24	60
6	MeOH	K2CO3	24	12
7	THF	K2CO3	24	25
8	DCM	K2CO3	24	19
9	Acetonitrile	K2CO3	24	15