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. Author manuscript; available in PMC: 2012 Aug 15.
Published in final edited form as: J Immunol. 2011 Jul 15;187(4):1977–1985. doi: 10.4049/jimmunol.1101247

Figure 1. Susceptibility to IRBP vs. S-Ag induced EAU in various HLA class II Tg mice.

Figure 1

The indicated strains of HLA transgenic mice were immunized with a uveitogenic protocol of either IRBP or S-Ag, as described in Methods. (A) IRBP induced EAU; (B) S-Ag induced EAU. The data are combined from five independent experiments. Shown is severity of EAU assessed by histopathological analysis of eyes collected 24 – 28 days after immunization. Each point represents one mouse (average score of both eyes). Horizontal one denotes the mean score of the group.