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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Biol Psychiatry. 2011 Apr 30;70(5):425–433. doi: 10.1016/j.biopsych.2011.03.017

Figure 4. Kappa opioid receptor (KOR) antagonism in the basolateral (BLA) and central (CeA) nuclei of the amygdala decreases fear-potentiated startle (FPS).

Figure 4

Microinfusions of the KOR antagonist JDTic or vehicle were administered 24 hr prior to FPS testing. JDTic in the BLA (A) or CeA (B) decreased FPS (mean ± S.E.M.; Dunnett’s tests), without affecting baseline startle (not shown). (C) JDTic in the striatum (STR) did not affect FPS (Student’s t test). (D) Summary of cannula tip placements in the BLA (black circles; n=10–12/group), CeA (gray triangles; n=5–8/group), or STR (gray squares; n=6–7/group). *P<0.05 vs. vehicle. Images in D published in The Rat Brain in Stereotaxic Coordinates, 3rd ed. (93) and reprinted with permission, Copyright Elsevier (1996).